Nitroglycerin Ointment (for Anal Fissures)
Formulation: Nitroglycerin 0.125%, 0.2%, and 0.4%
Cream for treating anal fissures.
Description: Nitroglycerin dilates blood vessels to help improve anal fissures. The medication works to relax smooth muscle of the internal anal sphincter. This allows the tear in the anus to heal as blood flow improves. An anal fissure is a tear in the anal canal that frequently is related to spasms and tension of the internal anal sphincter. The anal sphincter is a group of muscles located at the end of the rectum. The internal anal sphincter provides much of the resting pressure of the anal canal which is important for bowel continence.
The use of a topical nitroglycerin ointment can greatly improve the healing time for an anal fissure and possibly prevent the fissure from becoming chronic.
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